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March 19, 2024

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It is now clear that Omicron can infect those with previous COVID-19 infection and natural immunity, as well as those fully vaccinated, and of course, the smaller fraction of individuals who are COVID-19 naive. While we have a mix of prolonged Delta cases and in many cases with moderate to severe symptoms, Omicron syndrome has been characterized as mild and brief with a notable absence of pulmonary symptoms.  

How did Omicron secure this large and growing ecological niche? We have learned that Omicron replicates at a 70-fold increased rate over Delta. Additionally, Omicron appears to generate immunity not only against itself, but also against Delta, the prior dominant variant. So as Omicron moves through the population rapidly, it provides a larger immunologic barrier to further Delta expansion and will likely work to bring down the Delta curve while the Omicron peak continues to build in a sharply upward and hopefully brief spike in cases. 

Additionally, modeling studies suggest that the dual Lilly (bamlanivimab and etesevimab) and Regeneron (casirivimab and imdevimab) monoclonal antibody products are unlikely to neutralize Omicron, leaving only sotrovimab by GSK as the remaining monoclonal antibody in our armamentarium for high-risk seniors who develop severe symptoms with Omicron. 

While many have said, Omicron is “mother nature’s booster,” it will be some time before we can celebrate as the blend of Delta and Omicron, which present with similar features but take two separate clinical courses, is bound to confuse both the patients and the doctors trying to grapple with this new clinical reality.   

This week’s program has a new song from RC The Rapper, who teams up with First Nations Country Music Singer Jordan Shingoose with the new single “Home,” which is about home and the importance of medical freedom. We also have the rockstar of evidence-based medicine, Dr. Paul Alexander who will update us on the evidence for natural immunity and the emergence of Omicron and how this changes the calculus for the global COVID-19 vaccine program.

So let’s get real, let’s get loud, on America Out Loud Talk Radio, this is The McCullough Report!

The McCullough Report: Sat/Sun 2 PM ET Encore 7 PM – Internationally recognized Dr. Peter A. McCullough, known for his iconic views on the state of medical truth in America and around the globe, pierces through the thin veil of mainstream media stories that skirt the significant issues and provide no tractable basis for durable insight. Listen on iHeart Radio, our world-class media player, or our free apps on AppleAndroid, or AlexaEach episode goes to major podcast networks early in the week and can be heard on-demand anywhere in the world.

 https://www.medrxiv.org/content/10.1101/2021.11.11.21266068v2
 https://www.med.hku.hk/en/news/press/20211215-omicron-sars-cov-2-infection
 https://fortune.com/2021/12/28/omicron-infection-delta-covid-strain-resistance-south-africa-study-ahri/
 https://www.youtube.com/watch?v=TwvSSwpVqkc

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MANY VOICES, ONE FREEDOM: UNITED IN THE 1ST AMENDMENT

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Tammy Rainone
Tammy Rainone
2 years ago

I recently had Covid. I don’t know for sure if what omicron but it was milder than I’ve heard of other variants. It was more than 1 day for sure. About 7 days of feeling completely exhausted, weak and miserable. My sister has it now and is also completely exhausted and weak as well. She is on day 5 now. How do We know which variant We have? .

Kryptos
Kryptos
2 years ago

Many thanks to America out loud and Dr. McCullough!
Not all Church Leaders were under the psychosis:
Russian Orthodox Christian Bishop Andrei Erastov, Australia in February 25, 2021:

‘Most importantly, we must all understand that what is happening is a grandiose world-wide deception with unknown to us, but undoubtedly the most sinister, satanic aims.
The global vaccination, riding on the wave of hysterical fear caused by a year-long unceasing propaganda is, obviously, one of the cardinal elements of this satanic plan…
‘That’s why we strongly advise our parishioners not to agree to be vaccinated against the coronavirus – under any circumstances, even if this may bring about physical hardships, such as loss of job.’
https://archive.fo/51ds3

Bishop Andrei Erastov was formally an Iconographer and created these Icons:

Daniel Verona
Daniel Verona
2 years ago

Hello! I am submitting this original song for the music section of your podcast. I am a musician and producer here in Dallas and I recently worked with a local vocalist to write this prayerful worship song. Thought it would fit the podcast well since it is uplifting and hopeful.

https://soundcloud.com/danieljverona/mirror

Thank you for your work in discussing all these issues related to Covid!

All the best,
Daniel Verona

Chris
Chris
2 years ago

There’s a study suggesting robust T-Cell immunity also against Omicron: https://www.medrxiv.org/content/10.1101/2021.12.26.21268380v1

Keiko
Keiko
2 years ago

My husband is working at hospital and he claims 90% of Covid patients are unvaccinated. How do you explain this? He is coercing me and my daughter to get vaccination.

Mirjana
Mirjana
Reply to  Keiko
2 years ago

As a statistician I can tell you that what your husband is observing is due to The Law of Large numbers.
I will explain. We all know that if you flip coin say 10 times you EXPECT to get 5 heads and 5 tails. That is what probability says should happen as TRUTH is both heads and tails have 50% chance of occuring.
However, 10 is small number so if you try to flip coin 10 times (ask your husband to do this) you may get 9 heads and 1 tail or say 7 tails and 3 heads. This in your little experiment you will not get 50% of the time head and 50% of the time tail. However if you were to flip coin 100,000 times, you should get close to 50,000 heads and 50,000 tails. This is the law of large numbers. You need very large sample, only then your sample results will be close to TRUTH. The larger the sample the closer to truth your results get
So whatever your husband is observing is due to small sample size, he probably did not see 100,000 patients.
Public England Health publishes monthly reports and in their September report they stated that from February 1,2021 to September 1,2021, they had total of about 593,000 positive cases. 47% were fully vaccinated (around 280,000) and 43% were unvaccinated. They did not have vaccination status on 10% of patients.
I would go by results of the study that includes 593,000 patients not by what one doctor sees which is probably sample size less that 10,000.

Keiko
Keiko
Reply to  Mirjana
2 years ago

Thank you for the explanation. I feel me just better being unvaccinated.

Richard Eisenberg
Richard Eisenberg
Reply to  Keiko
2 years ago

Do not get vaccinated!

Last edited 2 years ago by Richard Eisenberg
Keiko
Keiko
Reply to  Richard Eisenberg
2 years ago

I won’t, and I will do all my best to prevent my daughter from being vaccinated. Thank you

MrsJackson33
MrsJackson33
2 years ago

Thank you for all that you do. I have LEARNED SO MUCH since a good friend of like mindedness sent me your podcast. You are an amazing doctor and an incredible teacher. I wish more and more people would listen to you and understand. The world will soon see what you knew all along. I keep telling people to listen to you. The sheep will wake.

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