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October 25, 2021

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Risks of Vaccines for Those Recovered from COVID-19 – Krammer, Raw & Mathioudakis

by | Sep 12, 2021 |

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There is recent research on the fact that the COVID-19 vaccine is dangerous for those who have already had COVID-19 and have recovered with inferred robust, complete, and durable immunity. These patients were excluded from the FDA-approved clinical trials performed by Pfizer, Moderna, and J&J. From these trials, the safety profile was unknown when the products for approved for Emergency Use Authorization in 2020. There has been no study demonstrating clinical benefit with COVID-19 vaccination in those who have well documented or even suspected prior COVID-19 illness.

A medical study of United Kingdom healthcare workers who had already had COVID-19 and then received the vaccine found that they suffered higher rates of side effects than the average population. Rachel K. Raw, et al., Previous COVID-19 infection but not Long-COVID-19 is associated with increased adverse events following BNT162b2/Pfizer vaccination, medRxiv (preprint), (last visited June 21, 2021).

Previous COVID-19 infection but not Long-COVID is associated with increased adverse events following BNT162b2/Pfizer vaccination

The test group experienced more moderate to severe symptoms than the study group that did not previously have COVID-19.

The symptoms included fever, fatigue, myalgia-arthralgia, and lymphadenopathy. Id. Raw found that in 974 individuals who received the BNT162b2/Pfizer vaccine, those with a prior history of SARS-CoV-2 or those who had positive antibodies at baseline had a higher rate of vaccine reactions than those who were COVID-19 naive.


Mathioudakis et al. reported that in 2020 patients who underwent vaccination with either mRNA-based or vector-based COVID-19 vaccines, COVID-19-recovered patients who were needlessly vaccinated had higher rates of vaccine reactions.


Krammer et al. reported on 231 volunteers for COVID-19 vaccination, 83 of whom had positive SARS-CoV-2 antibodies at the time of immunization. The authors found: “Vaccine recipients with preexisting immunity experience systemic side effects with a significantly higher frequency than antibody naïve vaccines (e.g., fatigue, headache, chills, fever, muscle or joint pains, in order of decreasing frequency, P < 0.001 for all listed symptoms, Fisher’s exact test, two-sided).”


Robust spike antibody responses and increased reactogenicity in seropositive individuals after a single dose of SARS-CoV-2 mRNA vaccine

Natural Immunity to COVID-19

To my knowledge, there are no studies that demonstrate the clinical benefit of COVID-19 vaccination in COVID-19 survivors or those with suspected COVID-19 illness or subclinical disease who have laboratory evidence of prior infection.

It is my opinion that SARS-CoV-2 causes an infection in humans that results in robust, complete, and durable immunity, and is superior to vaccine immunity which by comparison has demonstrated massive failure including over 10,000 well-documented vaccine failure cases as reported by the CDC before tracking was stopped on May 31, 2021.

There are no studies demonstrating the clinical benefit of COVID-19 vaccination in COVID-19 survivors, and there are three studies demonstrating harm in such individuals. Thus, it is my opinion that the COVID-19 vaccination is contraindicated in COVID-19 survivors, many of whom may be in the student population.

Multiple laboratory studies conducted by highly respected U.S. and European academic research groups have reported that convalescent mildly or severely infected COVID-19 patients who are unvaccinated can have greater virus-neutralizing immunity—especially more versatile, long-enduring T- cell immunity—relative to vaccinated individuals who were never infected.

See Athina Kilpeläinen, et al., Highly functional Cellular Immunity in SARS-CoV-2 Non- Seroconvertors is associated with immune protection, bioRxiv (preprint),

Highly functional Cellular Immunity in SARS-CoV-2 Non-Seroconvertors is associated with immune protection

(last visited June 26, 2021); Tongcui Ma, et al., Protracted yet coordinated differentiation of long-lived SARS-CoV-2-specific CD8+ T cells during COVID-19 convalescence, bioRxiv (preprint),

Protracted yet coordinated differentiation of long-lived SARS-CoV-2-specific CD8+ T cells during COVID-19 convalescence

(last visited June 26, 2021); Claudia Gonzalez, et al., Live virus neutralisation testing in convalescent patients and subjects vaccinated against 19A, 20B, 20I/501Y.V1 and 20H/501Y.V2 isolates of SARS-CoV-2, medRxiv (pre-print), (last visited June 21, 2021); Carmen Camara, et al. Differential effects of the second SARS-CoV-2 mRNA vaccine dose on T cell immunity in naïve and COVID-19 recovered individuals, bioRxiv (preprint),

Differential effects of the second SARS-CoV-2 mRNA vaccine dose on T cell immunity in naïve and COVID-19 recovered individuals

(last visited June 26, 2021); Ellie N. Ivanova, et al., Discrete immune response signature to SARS-CoV-2 mRNA vaccination versus infection, medRxiv (preprint),

Discrete immune response signature to SARS-CoV-2 mRNA vaccination versus infection

(last visited June 26, 2021); Catherine J. Reynolds, et al., Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose, (preprint),

Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose

(last visited June 21, 2021); Yair Goldberg, et al., Protection of previous SARS-CoV-2 infection is similar to that of BNT162b2 vaccine protection.

Cleveland Clinic studied their employees for the effects of natural immunity in unvaccinated people. Nabin K. Shrestha, Patrick C. Burke, Amy S. Nowacki, Paul Terpeluk, Steven M. Gordon, Necessity of COVID-19 vaccination in previously infected individuals, medRxiv (preprint),

Necessity of COVID-19 vaccination in previously infected individuals

(last visited June 21, 2021). They found zero SARS-CoV-2 reinfections during a 5-month follow-up among n=1359 infected employees who were naturally immune remained unvaccinated and concluded such persons are “unlikely to benefit from COVID-19 vaccination.”Among those who were vaccinated, unlike the naturally immune, there were vaccine failure or breakthrough cases of COVID-19.

An analysis by Murchu et al. demonstrated in 615,777 individuals, which included well-documented COVID-19 as well as subclinical infections with positive serologies, there was a negligible incidence (<1%) of COVID-19 over the long term. Murchu found no evidence of waning immunity over time, suggesting no possibility that future vaccination would be indicated for any reason.

Quantifying the risk of SARS-CoV-2 reinfection over time

A recently published article in Nature reported that prior infection induces long-lived bone marrow plasma cells, which means the antibodies to prevent reinfection of COVID-19 are long-lasting. Jackson S. Turner et al. SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans (May 24, 2021).

SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans

Dr. Peter McCullough

Dr. Peter McCullough is an internist, cardiologist, epidemiologist, in academic medical practice in Dallas, Texas, USA. He maintains ABIM certification in internal medicine and cardiovascular diseases. He manages common infectious diseases as well as the cardiovascular complications of both the viral infection and the injuries developing after the COVID-19 vaccine.

Since the outset of the pandemic, Dr. McCullough has been a leader in the medical response to the COVID-19 disaster and has published "Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19) Infection," the first synthesis of sequenced multidrug treatment of ambulatory patients infected with SARS-CoV-2 in the American Journal of Medicine and subsequently updated in Reviews in Cardiovascular Medicine.

He has 51 peer-reviewed publications on the infection and has commented extensively on the medical response to the COVID-19 crisis in TheHill and on FOX NEWS Channel.

On November 19, 2020, Dr. McCullough testified in the US Senate Committee on Homeland Security and Governmental Affairs and throughout 2021 in the Texas Senate Committee on Health and Human Services, Colorado General Assembly, New Hampshire Senate, and South Carolina Senate concerning many aspects of the pandemic response. Dr. McCullough has had 18 months of dedicated academic and clinical efforts in combating the SARS-CoV-2 virus and in doing so, has reviewed thousands of reports, participated in scientific congresses, group discussions, press releases, and has been considered among the world's experts on COVID-19.

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Brenda
Brenda
1 month ago

Thank you, thank you, thank you! We SO need more mainstream info on natural immunity for awareness. One of my best friends is Covid recovered and does not want the vaccine as she trusts her own natural immunity. Now she’s at the inevitable crossroads of having to decide whether to “roll the dice” and get vaccinated due to the mandates. These are horrific circumstances for so many people.

Now I hear there are even more restrictions being placed on doctors and the narrative they must follow or face dire consequences. What a tragedy. It’s doctors like yourself and the other select few, that people like myself ( who have decided to now take their health into their own hands) who are so appreciative of all of your hard work.

Keep up the fight!

Best regards,
Brenda

Ely
Ely
1 month ago

Dear Dr. McCullough, the recent Maccabi (ultra-pro-vax Israeli HMO) supported study: “Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections” spoke of the superiority of natural immunity, giving it wide coverage worldwide (particularly among anti-vaccine advocates – classic propaganda tactics). Yet the bottom line of the conclusion is: “Individuals who were both previously infected with SARS-CoV-2 and given a single dose of the vaccine gained additional protection against the Delta variant.” I have no expertise in this field, but thought you should know.
https://www.medrxiv.org/content/10.1101/2021.08.24.21262415v1

Terry
Terry
Reply to  Ely
1 month ago

Though that “additional protection” is true. the numbers are so tiny that it’s numerically insignificant.

Ruth Donnell
Ruth Donnell
Reply to  Ely
10 days ago

Dear Doctor McCullough, I am a register nurse and contracted Covid from a patient after given the wrong mask! on Jan 5 2021 my test was positive ! I was off work with COVID until Feb 1,2021 ! On 8/12/2021 I got the Pfizer vaccine because if the mandate! The next day I was SOB, had a sore throat, headache! The list goes on ! I have more doctor bills than I had in my life! I’m a healthy person with occasional asthma spring and summer! These reactions caused a rash like a sun burn on my left arm where I got the shot! Then it move to my chest but was more like hives , then the next day the rash went to my right lower leg as a large circle and itched so bad! I hacked up this nasty big sputum with blood specks all over in it! My doctor would not analyze it. I developed a swelling left leg that felt like a fracture! Doppler were negative for a DVT! Then petechiae but platelets we’re normal! She tested me for lupusa d it was negative! The immunologist I went to was very argumentative and handed me an article on consensus about the vaccine risk versus benefits and he said I didn’t have reactions because it was not a anaphylactic reaction! Can you help me please. No one will admit that the vaccine was harmful to me!

Marilyn
Marilyn
1 month ago

My sister is a long-haul COVID survivor(since March 2020) (main comorbidity is being overworked at age 63 and a type A+ personality) who had a pacemaker installed to regulate heart rate (which went very low when hiking). Due to the pressure of her daughter who would not allow her to see the grandchildren without the jab, she recently (August 2021) took Jab#1 and has had very bad reactions (brain fog, kidney issue, “funky” nasal scent, fatigue) for 2 weeks.
What does this study say about the jab and long-haulers?

Fred Grube
Fred Grube
Reply to  Marilyn
1 month ago

I’m not a doctor, so I’m just repeating things I think I’ve heard. It seems like in general though vaccines should be avoided while the patient is sick. And since the immunity of recovered covid patients is robust, complete, and durable, it would seem therefore seem vaccination would not be advised.

And you might ask about Fluvoxamine. It seems like it can penetrate the blood brain barrier and also has some anti inflammatory properties, so maybe it would help her brain fog.

Andrea
Andrea
1 month ago

Do you have a list of all the studies that show natural immunity is sufficient and that they do not need a vaccine. I am trying to help inform people. I have been searching all over and there are things here and there . I would love a list. Do you have one compiled or can you send me to a site that has one. I have looked at the links above and listen to all your podcasts. Thank you Dr. C!!

Miller
Miller
25 days ago

Please help me understand….I see this at the bottom of the BioRXiV reprints that some of the above research articles above are opening up in is supported by Chan Zuckerberg Initiative. Question is are the studies in the BioRxIV sites funded by Zuckerberg or is this a reprinting site that always readers to access the articles for no cost? Seeing as how they sensor FakeBook I want to make sure these studies are unbias. I see some articles claim no conflicts of interest. Thanks

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